Glucose and cholesterol induce abnormal cell divisions via DAF-12 and MPK-1 in C. elegans
نویسندگان
چکیده
منابع مشابه
MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module.
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In the nematode Caenorhabditis elegans, neurons are generated from asymmetric divisions in which a mother cell divides to produce daughters that differ in fate. Here, we demonstrate that the gene pig-1 regulates the asymmetric divisions of neuroblasts that divide to produce an apoptotic cell and either a neural precursor or a neuron. In pig-1 mutants, these neuroblasts divide to produce daughte...
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ژورنال
عنوان ژورنال: Aging
سال: 2020
ISSN: 1945-4589
DOI: 10.18632/aging.103647